Peptidases of Erythrocytes

Signal peptidases.

Evolutionary families of peptidases.

The available amino acid sequences of peptidases have been examined, and the enzymes have been allocated to evolutionary families. Some of the families can be grouped together in 'clans' that show signs of distant relationship, but nevertheless, it appears that there may be as many as 60 evolutionary lines of peptidases with separate origins. Some of these contain members with quite diverse pep...

Of peptides and peptidases: the role of cell surface peptidases in cancer.

Introduction The renin-angiotensin system has been studied for over three decades in relation to cardiovascular and renal physiology. Angiotensin II (Ang II), the central product of the renin-angiotensin system, functioning through the Ang II type 1 receptor has been shown to exert numerous effects, including stimulating cell growth, inducing gene expression of various growth factors (i.e., bas...

Serum peptidases in myocardial infarction.

The activities of three peptidases, glycyl peptidase, y-glutamyl transpeptidase, and leucine aminopeptidase, were determined at regular intervals in the sera of 5I patients with myocardial infarction. The activity of glycyl peptidase rose significantly on the second or third day after infarction, while significant increase in y-glutamyl transpeptidase and leucine aminopeptidase occurred by the ...

Trypanosoma cruzi Peptidases: An Overview

Peptidases are a group of enzymes which have a catalytic function that is to hydrolyze peptide bonds of proteins. The enzymes that hydrolyze peptide bonds at the aminoor carboxyterminus are classified as exopeptidases, and those that cleave peptide bonds inside the polypeptide are endopeptidases. Endopeptidases, such as cysteine-, metalo-, serineand threonine peptidases as well as some exopepti...